CONFERENCE SCHEDULE
To see the abstracts, click here
Revised Conference Schedule
Thursday, May 19, 2005
1:00 - 3:00 Registration - Foyer of the Sonoran Ballroom
Scientific Session 1 - Sonoran Ballroom
Environment and Gene-Environmental Interactions
in Cardiovascular Defects
Session Chairs: Raymond Runyan and Steven Fisher
3:00 - 3:20 Clustering of Congenital Heart Defects is Sex Specific
Karen S. Kuehl (1) and Christopher A. Loffredo (2), (1) George Washington University Medical School, (2) Georgetown University Medical School
3:20 - 3:40 Folic Acid Prevents Conotruncal Malformations in Folbpl Knockout Mice: Role of Folate in Cardiac Neural Crest Cell Survival and Migration
J. Gelineau-van Waes (1), F. Aleman (1), J. Maddox (1), L. Tang (2), L. Bauer (1), T. Rosenquist (1), R.H. Finnell (1,2), (1) Univ.
of Nebraska Medical Center, (2) Institute of Biosciences and Technology, Texas A&M University System Health Science Center
3:40 - 4:00 Effects of Trichloroethylene (TCE) and its Metabolite, Trichloroacetic Acid (TCAA), on Expression of Vimentin in the Rat H9c2 Cell Line
Ornella Selmin, Patricia A. Thorne, Raymond B. Runyan,
University of Arizona
Scientific Session 2 - Sonoran Ballroom
Imaging the Developing Heart
Session Chairs: Carol Gregorio and Cecelia Lo
4:00 - 4:20 A Time-Lapse Study of Direct Visualization of the Embryonic and Cardiovascular Development in the Chick Embryo in Shell-Less Culture Over 9 Days
T.M. Yelbuz (1), O. Tutarel (1), K. Norozi (1), O. Hornung (2),
G. Orhan (1), P. Wübbolt-Lehmann (1), A. Wessel (1),
(1) Hannover Medical School, Hannover, Germany, (2) Mechatronik-Zentrum, Universität Hannover, Hannover, Germany
4:20 - 4:40 Dynamic Imaging of Cardiovascular Mechanics
M. E. Dickinson, E.A.V. Jones, A.S. Forouhar, M. Liebling, J. Chen, S.E. Fraser, and M. Gharib, California Institute of Technology & University of California, San Diego
4:40 - 5:00 Novel X-linked Mutation Causing Hypertrophic Cardiomyopathy: Ultrasound Phenotyping Using Gated vs.
Non-gated High Frequency Echocardiography
L. Leatherbury (1,2), Q. Yu1, D.L.Walker (1), B. Chatterjee1, B.H.Siegfried (1,3), M.A.Pappas (1), G.C. Slack (1), C.W.Lo,
(1) National Heart Lung Blood Institute/NIH1, (2) Children’s National Medical Center, (3) National Naval Medical Center
5:30 - 7:15 Opening Reception - Sonoran Ballroom Rooftop Pavilion
Music by Mariachi Sol Azteca
7:20-7:30 Introduction and Announcements
7:30 - 8:30 Keynote Talk Sponsored by the American Association of Anatomists and Steele Children's Center, Sonoran Ballroom
Christine E. Siedman, M.D., Harvard Medical School,
Boston, Massachusetts
Engineering Congenital Heart Disease Genes:
Big Insights from Small Models
8:30 - 10:00 Poster Preview and Social - Santa Catalina Ballroom
Friday, May 20, 2005
8:00 - 9:00 Continental Breakfast - Rooftop of the Sonoran Ballroom
9:00 - 10:50 Poster Session 1 - Santa Catalina Ballroom
(Those with odd number posters should attend)
Scientific Session 3 - Sonoran Ballroom
Early Heart Development
Session Chairs: Parker Antin and Thomas Bartman
10:50 - 11:10 Baf60c, a Cofactor of the SWI/SNF Chromatin Remodeling Complexes, Regulates Critical Aspects of Heart Development and Initiation of Left-Right Asymmetry at the Mouse Node
Jun K.Takeuchi (1), Heiko Lickert (2), Masamichi Yamamoto (3), Hisoshi Hamada (3), Janet Rossant (2), Benoit G. Bruneau (1),
(1) The Hospital for Sick Children, and University of Toronto, Canada, (2) Samuel Lunenfeld Research Institute and University of Toronto, Canada, (3) Osaka University, and CREST, Japan Science and Technology Corporation (JST), Osaka, Japan
11:10 - 11:30 Mesp Regulates Heart Cell Migration and Specification Through Separate Pathways in the Basal Chordate, Ciona Intestinalis
Brad Davidson, Weiyang Shi and Michael Levine, University of California, Berkeley
11:30 - 11:50 TBX5 Functions Within the Endoderm to Control the Timing of Cardiac Cell Commitment
Sarah Goetz and Frank L. Conlon, Carolina Cardiovascular Center, University of North Carolina
11:50 - 12:10 Differentially Directed Cell Movements Drive Heart Tube Assembly in Zebrafish
Nathalia Glickman, Huai-Jen Tsai*, and Deborah Yelon, Skirball Institute, NYU School of Medicine and *National Taiwan University, Taiwan
12:10 - 1:30 Lunch Break, Box Lunches - Sonoran Ballroom Patio
12:25 - 1:25 Presentations and Question and Answer Period with
Dr. Charlene Schramm, Program Officer, National Heart, Lung and
Blood Institute, NIH. Link to NIH information provided by Dr. Schramm.
Scientific Session 4 - Sonoran Ballroom
Heart Valve Development
Session Chairs: Scott Klewer and Joey Barnett
1:30 - 1:50 TGF-ß2 Regulates Epithelial-to-Mesenchymal Transformation (EMT) and Cushion Mesenchyme Differentiation by Controlling the Angiogenic Switch
Tom Doetschman (1), Jennifer Martin (1), Moying Yin (1), Sharon Pawloski (1), Kui Xu (1), Adriana Gittenberger de-Groot (2) Mohamad Azhar (1), (1) University of Cincinnati College of Medicine, (2) LUMC, The Netherland
1:50 - 2:20 Atrioventricular Cushion Transformation Is Mediated by ALK2 in the Developing Mouse Heart
Jikui Wang, Somyoth Sridurongrit, Marek Dudas, Penny Thomas, Andre Nagy and Vesa Kaartinen, Childrens Hospital Los Angeles and University of Southern California
2:20 - 2:40 BMP and FGF Regulatory Pathways Control Cell Lineage Diversification During Heart Valve Formation
Joy Lincoln, Christina Alfieri and Katherine E. Yutzey, Cincinnati Children’s Hospital Medical Center
2:40-3:00 Persistence of Cardiac Neural Crest Cells in the Semilunar and Aortoventricular Valves
Tomoki Nakamura, Melissa Colbert, and Jeffrey Robbins, Cincinnati Children’s Hospital Medical Center
3:00-3:30 Coffee Break
Scientific Session 5 - Sonoran Ballroom
Proepicardium, Epicardium, Coronary Vessels and Mouse Models of CHD
Session Chairs: Todd Camenisch and Charlie Little
3:30 - 3:50 Induction of the Proepicardium
Yasuo Ishii, Romulo Hurtado, Sharrell B. Lee and Takashi Mikawa, Weill Medical College of Cornell University
3:50 - 4:10 Regulation of Gene Expression During Early Coronary Vasculogenesis: Identification of a Vasculogenic DNA Enhancer
Ravi P. Misra, Tim J. Nelson, Mary Holtz, and Stephen Duncan, Medical College of Wisconsin
4:10 - 4:30 BMP Signaling is an Important Regulator of Proepicardial Marker Gene Expression in the Chick Embryo
Jan Schlüter (1), Jörg Männer (2), and Thomas Brand (3), (1) Technical University of Braunschweig, (2) University of Göttingen, (3) Cell and University of Würzburg, Germany
4:30 - 4:50 Wnt/beta-Catenin Signaling Pathway Regulates Epicardial Function
Monica Zamora and Pilar Ruiz-Lozano University of California, San Diego
4:50 - 5:10 Pbx Mutant Mice Provide a Multigenetic Model for Congenital Heart Disease
Ching-Pin Chang, Kryn Stankunas, Licia Selleri, Gerald R. Crabtree, Michael L. Cleary, Stanford University
5:10 - 5:30 Neurofibromin GAP-Related Domain Rescues Cardiovascular Defects of Nf1-Deficient Mice
Fraz A. Ismat (1), Min Min Lu (2), Jonathan A. Epstein (2). (1) The Children's Hospital of Philadelphia, (2) University of Pennsylvania School of Medicine
5:30-6:30 Socializer- Sonoran Terrace
Friday evening is free for dinner. Shuttle buses will be available for transportation to La Encantada Center where restaurants include North, Blue Point (seafood) and others. Also to the St. Phillips Plaza area restaurants which include Acacia, Zin Bistro, P.F. Chang, Vivace, Ruth's Steakhouse. Busses will leave approximately every 20 minutes from Westward Look Resort between 6:00 and 10:00 p.m.
Saturday, May 21, 2005
8:00 - 9:00 Continental Breakfast - Sonoran Ballroom Rooftop
9:00 - 10:50 Poster Session 2 - Santa Rita Ballroom
(Those with even numbered posters should attend)
Scientific Session 6 - Sonoran Ballroom
Myocardium Regulation, Differentiation and Structure
Session Chairs: Paul Krieg and Scott Baldwin
10:50-11:10 Transcriptional Regulation of Cardiac Gene Expression by Myocardin
Thomas E. Callis, Dongsun Cao, and Da-Zhi Wang, Carolina Cardiovascular Biology Center, University of North Carolina
11:10-11:30 A Novel Pleckstrin Homology Domain Protein, HADP1, is Required for Cardiovascular Development in Zebrafish
Joshua D. Wythe, Lisa D. Urness, Michael Jurynec, Mariko Sato, David J. Grunwald, H. Joseph Yost, Dean Y. Li, University of Utah
11:30-11:50 Molecular and Functional Roles of Jumonji in Cardiovascular Development
Taegyun Kim, Matthew R. Mysliwiec, Jooyoung Jung, Junqin Chen, and Youngsook Lee, University of Wisconsin Medical School
11:50- 12:10 Cell Cycle Regulation During Early Cardiogenesis by the AMPK Family Member, SNF1LK
Ngoc-Thinh Nguyen, Angela Stephenson, Sonia T. Walton, and Joseph C. Ruiz, Wells Center, Indiana University School of Medicine
12:10 - 1:00 Box Lunch
1:00 - 1:30 Business Meeting, Sonoran Ballroom.
Election of Representatives and Selection of 2008 Site
1:40 - 2:00 Structural and Signaling Functions of M-Band Proteins Stephan Lange, Nikos Pinotsis, Elisabeth Ehler, Matthias Wilmanns, Mathias Gautel and Jean-Claude Perriard. King's College London, United Kingdom, Swiss Federal Institute of Technology (ETH) Zurich, Switzerland, EMBL Hamburg, Germany
2:00 - 2:20 KLF13, a Novel GATA4 Cofactor, is Required in Xenopus Heart Formation Andelfinger G., Lavallee G., Nadeau M., Horb M., Nemer M. Institut de Recherches Cliniques de Montréal, Montréal, QC, Canada
2:20 - 2:40 NDRG2 and NDRG4 are Required in Early Development of the Heart Xianghu Qu, Kevin Tompkins, Lorene Batts, Bruce Appel, Scott Baldwin. Vanderbilt University Medical Center
2:40 - 3:00 Blood-Borne Stem Cells Differentiate Into Cardiac Lineages During Normal Development Ning Zhang, Wade Reardon, Deanna Mustin, Angela deAlmeida, Paul Mozdziak,* Leonard M. Eisenberg, David Sedmera. Medical University of South Carolina, *North Carolina State University
3:00-3:30 Coffee Break
Scientific Session 7 - Sonoran Ballroom
Neural Crest, Outflow Tract, and the Anterior Heart Field
Session Chairs: Michko Watanabe and Henry Sucov
3:30 - 3:50 Msx1 and Msx2 Regulate Cardiac Neural Crest Cell Fate and Function
Yi-hui (Eva) Chen, Mamoru Ishii, Hualin Fu, Henry M. Sucov, and Robert E. Maxson, Jr. University of Southern California
3:50 - 4:10 MEF2C Function is Required in the Anterior Heart Field for Outflow Tract Development
Brian L. Black, Michael P. Verzi, Eric J. Jaehnig, Michael D'Ambrosio, and David J. McCulley . University of California, San Francisco
4:10 - 4:30 Signaling Through Fgfr2-IIIb is Required for Outflow Tract Septation
Anita Petiot (1), Stephane Zaffran (2), Fanny Bajolle (2), Nigel Brown (3), Clive Dickson (1), Margaret E. Buckingham (2), Robert G. Kelly (4). (1) Cancer Research UK, London Research Institute, (2) Institut Pasteur, CNRS, Paris, France, (3) St. George’s Hospital Medical School, London, UK, (4) Institute of Developmental Biology of Marseilles, France
4:30 - 4:50 Hedgehog Signaling is Critical for Development of the Outflow Tract of the Heart M.M. Goddeeris (1), R. Schwartz (2) and E.N. Meyers (1). (1) Duke University Medical Center, (2) Baylor College of Medicine
4:50 - 5:10 The Tremblor Mutation Leads to Cardiac Fibrillation by Calcium Overload Adam Langenbacher, Yuan Dong, Xiaodong Shu, Jayoung Choi, Deborah Nicoll, Ken Philipson, Joshua Goldhaber and Jau-Nian Chen. University of California, Los Angeles
5:10 - 5:30 Cardiac Neural Crest Cells are Necessary for Compaction and Function of Developing Conduction System Bundles Abhijit Gurjarpadhye (1,2), Kenneth W. Hewett (1) , Charles Justus (1), Xuejun Wen (1), Margaret L. Kirby (3), David Sedmera (1), Robert G. Gourdie (1,2). (1) Medical University of South Carolina; (2) Clemson-MUSC, (3) Duke University Medical Center
5:30 - 5:50 Requisite, Sequential Functions of FGF8 During Anterior Heart Field Development, and Outflow Tract Septation
Eon Joo Park, Jaclyn Tygesen, Anne M. Moon
Departments of Neurobiology and Anatomy, and Pediatrics, University of Utah
6:00 - 10:00 Outdoor Barbeque with Awards. Music by Code Orange
Westward Look Corral area